Custom becomes crime, crime becomes custom

This thesis examines the changing relationship between customary activities of the poor and economic change. The social crime debate is used to illustrate the historical importance of informal economic activity, both as a survival strategy and as a means of protest. Key issues of the experience in Britain will be highlighted, and issues such as self-interest will be placed within community toleration. Ironically, social criminal activities are also in the wider interests of the class of people from which social criminals themselves originate. The change from Feudalism and the origin of capitalism (particularly industrial capitalism) created the working class. The peasantry were increasingly displaced from the land, and habits suitable for work paid in cash were inculcated and forced upon people. Customary agricultural practices were gradually whittled away, but the working class changed these into perquisites and new customary work-based appropriation. Protest became located within the official structures of the labour movement, and increasingly orientated around the wage form. The post World War II economic boom encouraged standardisation and stabilisation of products, and within society itself. The onset of economic crises, beginning in the late 1960s, had increasingly global effects, and involved new markets encouraged by European integration. This changed the nature of (un)employment relations, the composition of the working class, consumption demands and possibilities, as well as creating a large and growing informal economy. This new casual and opportunistic, official/unofficial labour market, has meant a resurgence of social crime as a normal feature of survival. Shoplifting, tobacco and alcohol smuggling will be theoretically and practically examined; social crime content assessed; and protest capacity explored. Informant narratives highlight these key features of our time. The thesis further argues that crime has returned as a central aspect of culture

A meta-narrative review of electronic patient records

This session comprises four papers that consider how systematic review methods may be developed in order to make the best use of complex evidence in education and health. The methods and approaches reflected upon in these papers are not drawn from a single research tradition, but share a common goal of broadening the methodological scope of systematic reviews and better understanding the utilisation of knowledge produced in this way. The first paper (Henry Potts) reports an ongoing review using a meta-narrative approach to make sense of the diverse sources of knowledge regarding electronic patient records. The review method has stressed the importance of understanding knowledge from within the research tradition in which it was produced; it is argued that this has important implications for the way that evidence is utilised in the policy making process. The second paper (Geoff Wong) reflects upon the experience of using an explicit realist approach in the synthesis of the evidence in Internet based learning. This realist synthesis offers a method of making sense of the highly heterogeneous and context dependent evidence which exists in this field thus enabling greater insights into what makes such educational interventions ‘work’. The third paper (Rod Sheaff) reports a review of the predominantly qualitative research literature on organisational structures and their impacts upon policy outcomes in health systems. A scoping study found 14389 relevant papers of which 1568 were selected for review. These studies were very variable in the amount and quality of the qualitative data, hence 'evidence', which they reported. The paper describes an attempt to adapt realist methods so as to synthesise such bodies of research in ways which take account of this variation in the strength of qualitative evidence. The fourth paper (Mark Pearson) draws upon the work of Donald Campbell and colleagues in order to gain a fuller understanding of how systematic reviews are utilised in the policy making process. It is argued that interpretive approaches to understanding policy making (such as rhetorical analysis) need to be tempered with a more nuanced understanding of research validity. The case is made that interpretive approaches not only can, but should, be melded with research validity to increase understanding of the policy making process

Localization of Two-dimensional Electron Gas in LaAlO3/SrTiO3 Heterostructures

We report strong localization of 2D electron gas in LaAlO3 / SrTiO3 epitaxial thin-film heterostructures grown on (LaAlO3)0.3-(Sr2AlTaO3)0.7 substrates by using pulsed laser deposition with in-situ reflection high-energy electron diffraction. Using longitudinal and transverse magnetotransport measurements, we have determined that disorder at the interface influences the conduction behavior, and that increasing the carrier concentration by growing at lower oxygen partial pressure changes the conduction from strongly localized at low carrier concentration to metallic at higher carrier concentration, with indications of weak localization. We interpret this behavior in terms of a changing occupation of Ti 3d bands near the interface, each with a different spatial extent and susceptibility to localization by disorder, and differences in carrier confinement due to misfit strain and point defects.Comment: 12 pages, 4 figure

A systematic review of electronic patient records using the meta-narrative approach: Empirical findings and methodological challenges.

Systematic reviews are central to the enterprise of evidence-based medicine (EBM). However, traditional ‘Cochrane’ reviews have major limitations, especially when dealing with heterogeneous methodologies or an applied setting. The meta-narrative review (see Soc Sci Med 2005; 61: 417-30) is one of several new methods that seek to address pragmatic policy-level questions via broad-based literature reviews. Inspired by Kuhn, meta-narrative review takes a historical and paradigmatic approach to considering different areas of research activity. As an interpretive tool, the approach seeks distinct research traditions, each with its own meta-narrative. We then use these ‘stories of how research unfolded’ as a way of making sense of a diverse literature. Incommensurability between different traditions is seen not as a problem to be lamented or resolved but as a window to higher-order explanations about the nuances of empirical data and what these nuances mean for different applied situations. Having originally developed the meta-narrative method for a study of the diffusion of innovations in healthcare, we are now applying it in a review of the electronic patient record (EPR) in an organizational context. We have collated some 600 papers and books across multiple research traditions including health informatics, information systems research, computer-supported cooperative work (CSCW) and sociology. This very contemporary topic area is raising interesting methodological questions. For example, the EPR literature does not comprise as cleanly delineable traditions for four main reasons: 1. Information and communications technology research is a particularly fast-moving field, so paradigm shifts are relatively common (e.g. the rise of CSCW out of human-computer interaction research). 2. In the electronic age, it is easy for researchers to explore beyond their own discipline and ‘borrow’ theories, ideas and methods from elsewhere. Journal editors may commission overviews from experts in another tradition; authors may explicitly address an audience in another tradition. Research traditions can begin to converge (e.g. papers bringing together CSCW, information systems research and STS). 3. Some researchers are adept ‘boundary spanners’, writing for a number of different academic audiences and adapting their theoretical pedigree to fit (e.g. Marc Berg). 4. Some traditions are characterized not by a single unified paradigm but by active dialogue between competing paradigms (e.g. ‘hard’ versus ‘soft’ perspectives on knowledge management). This work contributes to the STS literature by critically questioning the nature of rigour in secondary research. The EBM movement values ‘Cochrane’ reviews because they meet positivist criteria (e.g. they are rational, objective, replicable, data-led, and transferable across contexts). In contrast, the meta-narrative review is interpretive, reflexive, problem-oriented and work-led, and makes no claim to either replicability or transferability. Rigour is redefined in terms of plausibility, authenticity and usefulness – raising the radical suggestion that the evidence base for key policy decisions can never be set in stone. Systematic reviews are central to the enterprise of evidence-based medicine (EBM). However, traditional ‘Cochrane’ reviews have major limitations, especially when dealing with heterogeneous methodologies or an applied setting. The meta-narrative review (see Soc Sci Med 2005; 61: 417-30) is one of several new methods that seek to address pragmatic policy-level questions via broad-based literature reviews. Inspired by Kuhn, meta-narrative review takes a historical and paradigmatic approach to considering different areas of research activity. As an interpretive tool, the approach seeks distinct research traditions, each with its own meta-narrative. We then use these ‘stories of how research unfolded’ as a way of making sense of a diverse literature. Incommensurability between different traditions is seen not as a problem to be lamented or resolved but as a window to higher-order explanations about the nuances of empirical data and what these nuances mean for different applied situations. Having originally developed the meta-narrative method for a study of the diffusion of innovations in healthcare, we are now applying it in a review of the electronic patient record (EPR) in an organizational context. We have collated some 600 papers and books across multiple research traditions including health informatics, information systems research, computer-supported cooperative work (CSCW) and sociology. This very contemporary topic area is raising interesting methodological questions. For example, the EPR literature does not comprise as cleanly delineable traditions for four main reasons: 1. Information and communications technology research is a particularly fast-moving field, so paradigm shifts are relatively common (e.g. the rise of CSCW out of human-computer interaction research). 2. In the electronic age, it is easy for researchers to explore beyond their own discipline and ‘borrow’ theories, ideas and methods from elsewhere. Journal editors may commission overviews from experts in another tradition; authors may explicitly address an audience in another tradition. Research traditions can begin to converge (e.g. papers bringing together CSCW, information systems research and STS). 3. Some researchers are adept ‘boundary spanners’, writing for a number of different academic audiences and adapting their theoretical pedigree to fit (e.g. Marc Berg). 4. Some traditions are characterized not by a single unified paradigm but by active dialogue between competing paradigms (e.g. ‘hard’ versus ‘soft’ perspectives on knowledge management). This work contributes to the STS literature by critically questioning the nature of rigour in secondary research. The EBM movement values ‘Cochrane’ reviews because they meet positivist criteria (e.g. they are rational, objective, replicable, data-led, and transferable across contexts). In contrast, the meta-narrative review is interpretive, reflexive, problem-oriented and work-led, and makes no claim to either replicability or transferability. Rigour is redefined in terms of plausibility, authenticity and usefulness – raising the radical suggestion that the evidence base for key policy decisions can never be set in stone

The in vivo study of cardiac mechano-electric and mechano-mechanical coupling during heart development in zebrafish

In the adult heart, acute adaptation of electrical and mechanical activity to changes in mechanical load occur

Regional and developmental brain expression patterns of SNAP25 splice variants

SNAP25 is an essential SNARE protein for regulated exocytosis in neuronal cells. Differential splicing of the SNAP25 gene results in the expression of two transcripts, SNAP25a and SNAP25b. These splice variants differ by only 9 amino acids, and studies of their expression to date have been limited to analysis of the corresponding mRNAs. Although these studies have been highly informative, it is possible that factors such as differential turnover of the SNAP25 proteins could complicate interpretations based entirely on mRNA expression profiles

Development and initial testing of a Health Confidence Score (HCS)

Introduction Patients need to feel confident about looking after their own health. This is needed to improve patient outcomes and clinical support. With few suitable tools available to measure self-care health confidence, we developed and validated a short, generic survey instrument for use in evaluation and quality improvement. Methods The Health Confidence Score (HCS) was developed through literature review, patient and expert focus groups and discussions. This paper reports an initial survey (n = 1031, study 1) which identified some issues and a further face-to-face survey (n = 378, study 2) to test the construct and concurrent validity of the final version. Scores were correlated against the My Health Confidence (MHC) rating scale, howRu (health status measure) and relevant demographics. Results The HCS is short (50 words) with good readability (reading age 8). It has four items covering health knowledge, capability to self-manage, access to help and shared decision-making; each has four response options (strongly agree, agree, neutral disagree). Items are reported independently and as a summary score. The mean summary score was 76.7 (SD 20.4) on 0–100 scale. Cronbach’s alpha = 0.82. Exploratory factor analysis suggested that the four items relate to a single dimension. Correlation of the HCS summary score with MHC was high (Spearman r = 0.76). It was also associated with health status (Spearman r = 0.49), negatively with number of medications taken (r=–0.29) and age (r=–0.22) and not with ethnicity, having children or education level. Conclusions The HCS is short, easy to use, with good psychometric properties and construct validity. Each item is meaningful independently and the summary score gives an overall picture of health confidence

Conversion coefficients and band assignments in Ta-180

The conversion coefficients for several bandhead decays in Ta-180 have been measured using pulsed-beam techniques and the Yb-176(Li-7,3n)Ta-180 reaction. The spin and parity of the 520 keV Intrinsic state is established as 4(+) and several earlier assignments are confirmed. Two-quasiparticle configurations for the 520 and 592 keV states are discussed and following reanalysis of the band properties, a consistent interpretation is reached. The 520 keV 4(+) state is associated with the favored coupling of the nu 1/2(-)[521]x pi 9/2(-)[514] configuration while the 592 keV (5(+)) state is identified with the nu 1/2(-)[510]x pi 9/2(-)[514] configuration

Occurrence of a chiral-like pair band and a six-nucleon noncollective oblate isomer in ¹²⁰I

We report for the first time two distinctive features in the odd–odd nucleus 120 I: a pair of doublet bands and a high-spin isomer built on the πh11/2νh11/2 configuration. For producing the excited states of 120 I, a fusion-evaporation reaction 118 Sn( 6 Li, 4n) at E =lab48 MeV was employed. The beam was provided by the 14UD tandem accelerator of the Heavy Ion Accelerator Facility at the Australian National University. The observed doublet structure built on the positive-parity states is the first case and unique in isotopes with Z=53 . The emerging properties are indicative of the known chiral characteristics, leading to a doubling of states for the πh11/2νh11/2 configuration. In contrast, the high-spin isomer with a half-life of 49(2) ns at spin-parity Jπ=25+ can be explained in terms of a noncollective oblate structure with the full alignment of six valence nucleons outside the 114 Sn core: three protons (g7/2)1(d5/2)1(h11/2)1 and three neutrons (h11/2)3 . This is an outstanding case that reveals a pure single-particle structure consisting of equal numbers of valence protons and neutrons outside the semi-double shell closure of 114 Sn with Z=50 and N=64 .Dr. C. Yuan acknowledges the National Natural Science Foundation of China (11775316